Students and exhausted workers have been abusing stimulants for decades. But these days, if you're keen to feel sharper, and work for longer, the drugs available are more effective than they once were - and less likely to make you feel awful afterwards. No wonder then that the abuse of pills such as Ritalin and modafinil is becoming a major problem. Katharine Hibbert reports on the rise of cognitive-enhancing drugs - and doctors' fears over their long-term safety.
Linda Blair: Many people who have suffered from post-traumatic stress disorder seek psychological help. In North America, scientists are going further, looking for ways to alter memories neurochemically.
Children are often forgotten casualties of their parents' drug addiction. But Addaction, the charity born from a Guardian article 40 years ago this week, is helping families rebuild their lives. In the second of two special reports David Ward tells of one mother's salvation.
In 1967, Mollie Craven, the mother of a heroin addict, wrote an article in the Guardian appealing to readers to start a self-help group for addicts and their families. Now, 40 years later, Addaction is Britain's leading drug charity.
9.45am: GW Pharmaceuticals today signed up Japan's Otsuka
to develop and market its pioneering cannabis-based drug Sativex in the US. By Julia Kollewe.